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Gabapentin binds with high affinity to the α2δ (alpha-2-delta) subunit of voltage-gated calcium channels and it is proposed that binding to the α2δ subunit may be involved in gabapentin's anti-seizure effects in animals! Taking an old drug, combining it with another ingredient, and convincing the FDA to grant a monopoly on the “new” combo drug is a well-known Pharma trick: in 2013, Merck combined Zetia, its LDL-cholesterol lowering drug, with the generic version of Lipitor. Keep up the superb works guys I¡¦ve incorporated you guys to my blogroll?
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